The Hotwives of Orlando

• Casey Wilson come Tawny St. John: "The Trophy Wife"
• Danielle Schneider come Shauna Maducci: "The Bankrupt Overspender"
• Tymberlee Hill come Fenomeno "Phe Phe" Reed: "The Entrepreneur
• Andrea Savage come Veronica Von Vandervon: "The Cougar"
• Angela Kinsey come Crystal Simmons: "The Religious Zealot"
• Kristen Schaal come Amanda Simmons: "L'ex star infantile drogata"

Cast di supporto e ricorrente

• Paul Scheer come Matty Green
• Joey McIntyre come Heath
• Stephen Tobolowsky come Phil
• Matt Besser come Anthony
• Jerry Minor come Rodney
• Seth Morris come T.J.
• Dannah Phirman come Alli
• Sterling Knight come Billy
• Jeff Hiller come Antoine

Altre apparizioni di ospiti nella prima stagione includono "Weird Al" Yankovic, Kate Walsh, Rich Fulcher, Melissa Rauch, Kulap Vilaysack, Lauren Lapkus, e Horatio Sanz.